The National Cancer Institute, part of the National Institutes of Health, is considering granting an exclusive patent license to Kyverna Therapeutics. This license would allow Kyverna to use certain patented inventions to develop a therapy using chimeric antigen receptors (CAR) targeting CD19 for treating autoimmune diseases. The CAR technology uses CRISPR/Cas9-edited T cells to recognize and attack cells expressing the CD19 protein, potentially offering a new treatment option for diseases such as lupus nephritis. Comments or objections to this proposed license must be submitted by March 5, 2021.
Simple Explanation
The National Cancer Institute is thinking about giving a company called Kyverna Therapeutics special permission to use a smart technology that helps the body's own defenders, called T cells, find and destroy harmful cells in diseases like lupus. People can share their thoughts or ask questions about this decision until March 5, 2021.