The Food and Drug Administration (FDA) has announced a list of information collections that have recently received approval from the Office of Management and Budget (OMB), under the Paperwork Reduction Act of 1995. Each collection of information has a specific OMB control number and an expiration date for its approval. The FDA emphasizes that any information collection they conduct must display a valid OMB control number; otherwise, individuals are not required to respond to it. More details, including the supporting statements for these collections, can be found online.
Simple Explanation
The FDA has a list of forms and information they need people to fill out, and these forms were checked and approved to make sure they're okay to use. If you see a number on these forms, it means someone made sure they're alright to ask you to fill them out.