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The Food and Drug Administration (FDA) has announced that certain Food Contact Notifications (FCNs) are no longer effective because some manufacturers stopped using the listed substances for food contact in the U.S. The FDA is following a set process that allows them to determine when an FCN is no longer in use. They expect all remaining stocks of these substances, which were last produced or supplied before January 6, 2025, to be used up by June 30, 2025, as a measure to protect public health. The FDA updated its inventory of effective and no longer effective FCNs on their website.

In response to COVID-19, the Acting Secretary of Homeland Security issued a declaration on January 27, 2021, stating that a national emergency exists. This declaration directs the Transportation Security Administration (TSA) to implement measures to ensure the safety of individuals using or working in the transportation system. Consistent with previous orders and recommendations from the Centers for Disease Control and Prevention, one of the key actions is the requirement for people to wear masks on transportation and at transportation hubs to help reduce the spread of the virus.

The proclamation "Religious Freedom Day, 2021," issued by former President Donald J. Trump, emphasizes the protection and promotion of religious freedom as a fundamental right. It highlights the efforts of his administration over the past four years to support religious liberty both domestically and internationally. The document addresses various actions taken to uphold the rights of individuals and religious organizations and calls on Americans to celebrate religious freedom. It commemorates January 16, 2021, as Religious Freedom Day, encouraging activities that honor the nation's heritage of religious liberty.

The Food and Drug Administration (FDA) has released draft guidance for the industry on using Artificial Intelligence (AI) to aid in regulatory decisions for drugs and biological products. This guidance explains how AI can be used to produce credible information or data regarding the safety, effectiveness, or quality of these products. It emphasizes a risk-based assessment framework for AI models and encourages early consultation with the FDA to ensure compliance and credibility. The guidance and its proposed recommendations are open for public comment until April 7, 2025, allowing stakeholders to contribute their views on the outlined framework and engagement options with the FDA.

The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) is hosting a public webinar on Non-animal Approaches for Mixtures Assessment. The event is being organized by the National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) and will be held on January 26, 2021. Participants can join via WebEx to learn about new methodologies for assessing the safety of chemical mixtures. Interested persons need to register for the webinar between January 4, 2021, and the morning of the event to participate.

The Centers for Disease Control and Prevention (CDC) announced a closed meeting for the Disease, Disability, and Injury Prevention and Control Special Emphasis Panel. The meeting, which will be held on June 10, 2021, via web conference, is closed to the public due to the possibility of revealing confidential information and personal privacy concerns. The agenda for this meeting includes reviewing and evaluating grant applications related to potential risk factors for Amyotrophic Lateral Sclerosis (ALS). For more information, interested parties can contact Mikel Walters, Ph.D., the Scientific Review Officer.