FR 2025-04397

Overview

Title

Supplemental Evidence and Data Request on Improving the Management of Menopausal Symptoms in Perimenopausal and Early Postmenopausal Women: A Systematic Review

Agencies

ELI5 AI

The AHRQ wants people to share their studies about helping women who are starting to have menopause so they can learn how to best manage it. They want everyone to send their ideas by April 17, 2025, so they can make the review better.

Summary AI

The Agency for Healthcare Research and Quality (AHRQ) is seeking additional scientific information from the public to assist with a systematic review on managing menopausal symptoms in perimenopausal and early postmenopausal women. This review is being conducted by AHRQ's Evidence-based Practice Centers (EPC) Program to improve its quality by considering both published and unpublished relevant studies. People and organizations are invited to submit completed and ongoing study details, which should be public or able to be made public, by April 17, 2025. The review will explore questions related to the effectiveness and safety of treatments for menopausal symptoms, as well as individual and system-level factors influencing treatment.

Abstract

The Agency for Healthcare Research and Quality (AHRQ) is seeking scientific information submissions from the public. Scientific information is being solicited to inform our review on Improving the Management of Menopausal Symptoms in Perimenopausal and Early Postmenopausal Women: A Systematic Review, which is currently being conducted by the AHRQ's Evidence-based Practice Centers (EPC) Program. Access to published and unpublished pertinent scientific information will improve the quality of this review.

Type: Notice
Citation: 90 FR 12534
Document #: 2025-04397
Date:
Volume: 90
Pages: 12534-12539

AnalysisAI

The document in question is a formal notice from the Agency for Healthcare Research and Quality (AHRQ) seeking additional scientific information from the public to aid in a systematic review of managing menopausal symptoms in perimenopausal and early postmenopausal women. The aim is to incorporate both published and unpublished data to enhance the quality of this review. This request comes under the AHRQ's Evidence-based Practice Centers (EPC) Program.

General Summary

The AHRQ is conducting a systematic review to improve the management of menopausal symptoms in perimenopausal and early postmenopausal women. They seek information from the public, including details of scientific studies that have been completed or are ongoing, whether published or unpublished. Submissions can be made via email or mail by April 17, 2025. The review focuses on various treatments' effectiveness and safety and explores how individual and system-level factors impact treatment access and outcomes.

Significant Issues or Concerns

One issue within the document is the lack of clarity regarding the term "SEADs" in the context of the EPC SEADs Coordinator. Without an explanation, some readers may be left confused about the role or meaning of this designation.

Additionally, the requirement for information submissions to be borne by the submitter might dissuade some parties from contributing, especially those with limited resources. This financial burden could limit the range and diversity of data contributed, potentially affecting the review’s comprehensiveness.

The document contains repetitive content when soliciting information, which might cause confusion or discourage some individuals from submitting if they perceive the request as overly complex.

A further concern is the lack of explicit information on how the confidentiality of unpublished data will be maintained, which may discourage submissions due to privacy concerns.

Lastly, the document specifies a submission deadline yet omits guidance regarding submissions past the due date. This absence of information could lead to complications for late submitters, uncertain of whether their contributions would still be considered.

Impact on the Public and Stakeholders

Broadly, this systematic review presents an opportunity to enhance understanding of menopausal symptom management, potentially leading to improved health outcomes for women experiencing menopause. By gathering extensive scientific data, the review could result in more informed decisions regarding treatment options.

For specific stakeholders such as healthcare providers, researchers, and organizations involved in women's health, the review might encourage more evidence-based approaches in managing menopausal symptoms. However, the requirement for submissions to be public or publicly available could pose confidentiality challenges, particularly impacting private sector stakeholders concerned with proprietary information.

In conclusion, while the document aims to bolster research and treatment for menopausal symptoms, it must address key concerns about clarity, submission costs, and data confidentiality to maximize public and stakeholder engagement.

Issues

  • • The document does not explain what the term 'SEADs' in EPC SEADs Coordinator stands for, which could be unclear to some readers.

  • • The document mentions that all costs for complying with the request for information must be borne by the submitter, which might be prohibitive for some organizations and could limit the diversity of information submitted.

  • • The language requesting information from the public could be more concise and clearer, as it is somewhat repetitive in asking for details of studies.

  • • The document specifies that materials must be publicly available or able to be made public, but it is not clear how the confidentiality of unpublished data will be maintained.

  • • The document specifies a submission deadline but does not provide information on what happens to submissions sent after this date, which could lead to confusion among potential submitters.

Statistics

Size

Pages: 6
Words: 1,113
Sentences: 46
Entities: 59

Language

Nouns: 384
Verbs: 73
Adjectives: 62
Adverbs: 7
Numbers: 29

Complexity

Average Token Length:
5.53
Average Sentence Length:
24.20
Token Entropy:
5.25
Readability (ARI):
20.15

Reading Time

about 4 minutes