FR 2021-00353

Overview

Title

Importer of Controlled Substances Application: Medi-Physics, Inc. dba GE Healthcare

Agencies

ELI5 AI

Medi-Physics, Inc., also known as GE Healthcare, wants to bring a special kind of medicine ingredient, related to Cocaine, from outside the U.S. because they can't get it here. They need it to work on how to make and check their products properly, and people can share their thoughts or concerns about this until February 11, 2021.

Summary AI

Medi-Physics, Inc., which does business as GE Healthcare, has submitted an application to the Drug Enforcement Administration (DEA) to become an importer of specific controlled substances. The company intends to import small amounts of Ioflupane, which is an analogue of Cocaine, for research and development purposes, as the required form is unavailable in the U.S. Anyone wishing to comment or request a hearing on this application must do so by February 11, 2021. The DEA's approval will depend on compliance with specific regulatory standards.

Abstract

Medi-Physics, Inc. dba GE Healthcare has applied to be registered as an importer of basic class(es) of controlled substance(s). Refer to Supplemental Information listed below for further drug information.

Type: Notice
Citation: 86 FR 2456
Document #: 2021-00353
Date:
Volume: 86
Pages: 2456-2457

AnalysisAI

Summary of the Document

This document is a notice from the Drug Enforcement Administration (DEA) announcing an application by Medi-Physics, Inc., which operates under the brand GE Healthcare. The company is seeking permission to import small quantities of a controlled substance, specifically Ioflupane, which is an analogue of Cocaine. The purpose of this import is to assist in research and development tasks, such as validating production and quality control systems, and preparing for a potential submission of an investigational new drug application. Those who wish to comment on or object to this application have until February 11, 2021, to submit their feedback or request a hearing. The final decision will be based on specific legal standards.

Significant Issues and Concerns

There are several issues worth highlighting in this document:

  1. Lack of Evaluation Criteria: While the document outlines the process for submitting comments or objections regarding the application, it does not detail the criteria the DEA will use to evaluate these inputs. Understanding these criteria would benefit stakeholders wishing to voice their opinions.

  2. Need for Specific Analogues: The notice states that the required form of Ioflupane is unavailable in the U.S., prompting the need for import. However, it does not explain why the domestic supply cannot meet the needs of Medi-Physics, Inc. More context would clarify the necessity of this importation.

  3. Import Volume Unspecified: The exact quantity of Ioflupane to be imported is not mentioned. Knowing the scale of the import is important for assessing its potential impact.

Impact on the Public and Stakeholders

The broader public might be concerned with the importation of a substance related to Cocaine, due to its association with illegal drug use. However, the substance in question is intended strictly for scientific and research purposes, which may mitigate such concerns.

For stakeholders in the healthcare and pharmaceuticals industry, this application may positively impact research and development efforts for new medical treatments by providing necessary materials not otherwise available domestically. If approved, this could spur advancements in diagnostic technology or therapeutic procedures, ultimately benefiting patient care.

Conversely, domestic manufacturers of controlled substances might view this application as a signal of insufficient domestic manufacturing capabilities, potentially spurring discussions around increasing production within the United States.

Conclusion

Overall, while the application by Medi-Physics, Inc. addresses a gap in available research materials, the lack of specific details regarding the importation process and volume might cause concern. A clearer understanding of the evaluative criteria used by the DEA could help reassure stakeholders and the public about the regulatory oversight in place. As the process unfolds, the final decision could notably influence future practices in drug research and development, as well as domestic production strategies.

Issues

  • • The document provides detailed information about the process for submitting comments or objections, but does not explain what criteria will be used to evaluate these comments or objections. Clarity on this process might be beneficial.

  • • There is no explanation given as to why the specific analogues of Cocaine are necessary for the validation of production and quality control systems, beyond the statement of their unavailability domestically. Additional context could aid in understanding the necessity of the importation.

  • • The document does not explain why Ioflupane is not available in the required form within the domestic U.S. supply, which may raise questions about domestic production capabilities.

  • • The document does not specify the volume or quantity of Ioflupane to be imported, which could be relevant for understanding the scale of the importation.

Statistics

Size

Pages: 2
Words: 473
Sentences: 20
Entities: 52

Language

Nouns: 164
Verbs: 33
Adjectives: 21
Adverbs: 5
Numbers: 30

Complexity

Average Token Length:
4.79
Average Sentence Length:
23.65
Token Entropy:
4.89
Readability (ARI):
16.28

Reading Time

about a minute or two